Ideal for neurologists and other health care professionals who treat patients with neuromuscular diseases, Neuromuscular Case Studies, 2nd Edition, presents more than 100 cases of both common and rare neuromuscular disorders. Dr. Tulio E. Bertorini provides the latest tools and strategies for diagnosis and management that minimize disability and maximize quality of life for your patients, including up-to-date coverage of numerous recent advances in the field. Using a multidisciplinary approach, this practical text contains two parts: the first includes basic aspects of anatomy, physiology, diagnostic tests, and therapeutic strategies; the second describes specific cases and their diagnosis and management.
Key Features
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Presents a multidisciplinary approach to the management and therapeutic treatment of the full range of neuromuscular disorders and resulting complications.
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Covers the latest advances in the field, including genetic causes of hereditary diseases, new autoimmune diseases, and promising new therapies such as antisense oligonucleotides, gene therapies, and immunotherapy.
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Includes the wide range of disorders that fall under each disease classification (e.g., the Motor Neuron Diseases chapter includes all forms of spinal atrophy, ALS, neuropathies and myopathies, as well as disorders of neuromuscular transmission). In turn, each disease section includes diagnosis and evaluation, treatment, outcome, and suggested readings.
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Uses a reader-friendly format that takes you step by step through the diagnosis and treatment of neuromuscular disorders, from the basic anatomy and physiology of the nerve and muscle through to clinical evaluation, diagnostic testing, and therapy.
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Reviews the etiologies, pathogenesis, differential diagnosis, and management of each disorder, helping you not only recognize its presentation, but also determine the best treatment plan.
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Arranges case studies and indexes both by complaint and by diagnosis.
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Features full-color clinical images and diagrams — along with numerous diagnosis tools, tables and treatment algorithms throughout — that make complex concepts easier to understand and apply.
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Shares the knowledge and experience of an expert in clinical neuromuscular care.
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An eBook version is included with purchase. The eBook allows you to access all of the text, figures and references, with the ability to search, customize your content, make notes and highlights, and have content read aloud. Any additional digital ancillary content may publish up to 6 weeks following the publication date.
Author Information
By Tulio E. Bertorini, MD, Professor of Neurology and Pathology, University of Tennessee, Center for Health Science Center, Memphis; Chief of Neurology, Methodist University Hospital and Director, Wesley Neurology Clinic and Muscular Dystrophy and ALS Clinic, Memphis, TN, USA
1 Neuromuscular Anatomy and Function
2 Neurologic Evaluation and Ancillary Tests
3 Therapy in Neuromuscular Diseases
Case 1 An Elderly Woman With Numbness in the Hands
Case 2 A Diabetic Man With Arm Swelling, Pain, and Numbness
Case 3 A Diabetic Man With Hand Numbness and Fainting Spells
Case 4 A Man With Hand Pain
Case 5 A Woman With Hand Weakness, Numbness, and Pain After Cardiac Catheterization
Case 6 A Man Who Practices Karate and Has Forearm Pain
Case 7 A Man With a History of Polio Who Developed Hand Weakness and Numbness
Case 8 A Young Woman With Multiple Sclerosis and Hand Numbness
Case 9 A Woman With a Wrist Drop and a Mass in the Arm
Case 10 A Man With Bilateral Arm Weakness After Lumbar Surgery
Case 11 A Woman With Acute Onset of Shoulder Pain and Weakness
Case 12 A Man With Lymphoma and Numbness in the Fingers of One Hand
Case 13 A Woman With Arm Weakness After Treatment for Breast Cancer
Case 14 A Diabetic Man With Shoulder Pain and Weakness
Case 15 A Woman With Arm Weakness and a Skin Rash
Case 16 A Woman With Neck and Arm Pain
Case 17 A Woman With Neck Pain and a Weak Arm
Case 18 A Woman With Back Pain and Leg Weakness
Case 19 A Woman With Back Pain and Weakness
Case 20 A Woman With Back Pain and Unusual Nerve Conduction Tests
Case 21 A Man With Pheochromocytoma and Back Pain
Case 22 A Diabetic Man With Back and Leg Pain
Case 23 A Man With Leg Pain While Walking
Case 24 A Man With Foot Pain
Case 25 A Man With Unilateral Proximal Leg Weakness After Heart Catheterization
Case 26 A Woman With Uterine Cancer and Unilateral Leg Weakness
Case 27 A Man With Burning Sensations in the Thigh
Case 28 A Man With Weakness and Fasciculations in the Lower Extremities
Case 29 A Woman With Unilateral Facial Weakness
Case 30 A Diabetic Woman With Muscle Weakness and Ophthalmoplegia
Case 31 A Man With a Dropped Head
Case 32 A Man in the “Barrel”
Case 33A A Man With a Long History of Muscle Weakness in One Arm
Case 33B A Young Man With Longstanding Weakness in Both Arms
Case 34 A Man With Progressive Leg Muscle Weakness 20 Years After an Acute Paralysis
Case 35 A Man With One Large Calf
Case 36 A Man With Muscle Spasms and Elevated Serum Creatine Kinase
Case 37 A Man With Muscle Twitching and Poor Balance
Case 38 A Floppy Child
Case 39 A Man With Acute Areflexic Paralysis and Central Nervous System Symptoms
Case 40 A Man With Acute Muscle Weakness and Respiratory Failure
Case 41 A Young Woman With Acute Onset of Clumsiness and Ophthalmoplegia
Case 42 A Woman With Seafood Poisoning in Catfish Country
Case 43 A Woman With a Kingly Disease
Case 44 A Myasthenic Woman With Persistent Weakness
Case 45 A Woman With COVID-19 Infection and Quadriparesis
Case 46 A Man With Neck Pain and Numbness in the Hands
Case 47 A Woman With Peripheral Neuropathy and Frequent Falls
Case 48 A Woman With Progressive Four-Limb Paresthesias
Case 49 An Elderly Woman With Frequent Falls and Abnormal MRI
Case 50 A Man With Weakness in the Legs
Case 51 An Elderly Woman With Asymmetric Weakness and a Monoclonal Gammopathy
Case 52 A Man With Progressive Weakness and Fasciculations
Case 53 A Man With Diabetic Polyneuropathy Who Developed Rapidly Progressive Weakness
Case 54A An Older Man With Leg Numbness
Case 54B An Elderly Man With a Peripheral Neuropathy Like His Sister
Case 55 A Man With Progressive Lower Extremity Weakness and Monoclonal Gammopathy
Case 56 A Woman With a Neuropathy and Symptoms of a Central Nervous System Disease
Case 57 A Man With Progressive Weakness After a Gastroplasty
Case 58 A Diabetic Woman With Unilateral Proximal Leg Weakness and Pain
Case 59 A Diabetic Man With Bilateral Arm Weakness
Case 60 A Diabetic Man With Acute Onset of Pain and Swelling in the Thigh
Case 61 A Uremic Man With Burning Feet
Case 62A A Woman With Leg Numbness, Pain, Weakness, and Slow Nerve Conduction Velocities
Case 62B A Boy With Leg Weakness
Case 63 A Man With Hand Weakness and Numbness After Skiing
Case 64 A Man With Recurrent Foot Drop
Case 65 An Elderly Woman With Foot Drop and Hand Weakness
Case 66 A Woman With Rheumatoid Arthritis Who Developed Numbness and Pain in the Feet
Case 67 A Woman With Granulomatous Lesions in the Lungs and a Peripheral Neuropathy
Case 68 A Man With a Neuropathy, Weight Loss, and Lung Nodules
Case 69 A Woman With Difficulty Walking and Ataxia
Case 70A A Man With Progressive Neuropathy and Congestive Heart Failure
Case 70B A Woman With a Demyelinating and Axonal Neuropathy
Case 71 An Elderly Woman With a Progressive Neuropathy
Case 72A A Young Woman With Difficulty Swallowing
Case 72B A Young Woman With Intermittent Weakness and a Positive Family History of Similar Problems
Case 73 A Weak Woman With a Weak Baby
Case 74 A Woman With Muscle Weakness and Areflexia
Case 75 An Elderly Woman With Proximal Weakness
Case 76 An Elderly Woman With Ptosis, Areflexia, and Weakness
Case 77 A Young Woman With Distal Upper Extremity Weakness
Case 78 A Young Man With Episodic Weakness
Case 79 An African American Man With Hyperthyroidism and Acute Paralysis
Case 80 A Boy With Large Muscles, Leg Pain, and Elevated Serum Creatine Kinase
Case 81 A Woman With Proximal Muscle Weakness, Calf Hypertrophy, Heel Contractures, and Elevated Serum Creatine Kinase
Case 82 A Young Man With Distal Leg Wasting and Normal Sensation
Case 83 A Boy With Proximal Weakness and Cardiomyopathy
Case 84 A Woman With Droopy Eyelids and Difficulty Swallowing
Case 85 A Man With Facial and Shoulder Muscle Weakness
Case 86 A Boy Born Floppy With Severe Weakness and, Later, Contractures
Case 87 A Woman With Long-standing Weakness and Foot Deformities
Case 88 A Floppy Baby Who Later Developed Malignant Hyperthermia
Case 89 A Woman With Droopy Eyelids and Ophthalmoplegia
Case 90 A Man With Weakness and Swelling in the Neck
Case 91 A Woman With Muscle Pains and Dark Urine
Case 92 A Woman With Progressive Proximal Muscle Weakness
Case 93 A Sedentary Man With Acute Respiratory Failure and Myoglobinuria
Case 94 An Elderly Man With New Onset Weakness
Case 95 A Uremic Man With Proximal Muscle Weakness
Case 96 A Woman With Weakness, Elevated Cholesterol, and Serum Creatine Kinase Levels
Case 97 An Older Woman With Leg Weakness and Atrophic Muscle Fibers on Biopsy
Case 98A A Woman With Muscle Weakness and a Skin Rash
Case 98B A Child With Muscle Weakness and a Skin Rash
Case 99 A Man With Muscle Pains
Case 100A An Older Woman With Progressive Muscle Weakness
Case 100B An Elderly Man With Weakness Diagnosed as Having a Myopathy and a Neuropathy
Case 101 An HIV-Infected Man With Muscle Weakness and Spasms
Case 102 A Patient With Rapidly Progressive Muscle Weakness and Rather Elevated Creatine Kinase
Case 103 A Woman With Painful and Swollen Legs
Case 104 A Man With a Bent Spine
Case 105 A Man With Muscle Stiffness and Later With Diplopia
Case 106 A Woman With Muscle Cramps and Fasciculations
Case 107 A Young Man With Large and Stiff Muscles
Case 108 A Woman With Generalized Increased Insertional Activity on EMG
Case 109 A Boy With Short Stature, Small Jaw, Muscle Hypertrophy, and Stiffness
Case 110 An Elderly Woman With Muscle Spasms
Case 111 A Woman With Proximal Muscle Weakness and Neuromuscular Irritability
Case 112 A Woman With Focal Spontaneous Muscle Movements
Index of Cases by Diagnosis
Index
"This book provides an in-depth exploration of various neuromuscular disorders through a collection of detailed case studies. This second edition replaces the first, published in 2008." ©Doody’s Review Service, 2024, Ali A Saherwala, MD (Thomas Jefferson University), Doody’s Score: 91 - 4 Stars!
